Release Notes

Version history and data provenance

LATEST

January 2026 Release (v2.0)

2026-01-14

New Models

  • Added 45 Non-Small Cell Lung Cancer (NSCLC) lines.
  • Integrated 12 rare pediatric brain tumor models.

Data Updates

  • Updated RNA-Seq quantification using Gencode v44.
  • Standardized mutation calling pipeline (Mutect2).

June 2025 Launch (v1.0)

2025-06-01

Initial release of cCCLE database featuring 450+ validated cancer cell line models with whole-exome sequencing and transcriptomic data.

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